Aflibercept-Related Sterile Intraocular Inflammation Outcomes

Written by: Priya Sharma Vakharia, MD December 2019 Greenberg JP, Belin P, Butler J, et al. Aflibercept-Related Sterile Intraocular Inflammation Outcomes. Ophthalmology Retina 2019;3: 753-9. Sterile intraocular inflammation after intravitreal injections is a well-known but rare side effect. Sterile inflammation has been reported with all anti-vascular endothelial growth factor (VEGF) injections, typically occurring in clusters. […]

Single-Port Vitrectomy and “Oleodelamination” for the Management of Retinal Detachment Complicated by Proliferative Vitreoretinopathy

Written by: Edward H. Wood, MD November 2019 Svasti-Salee CR, Dawkins RCH, Poulson AV, Snead MP. Single-Port Vitrectomy and “Oleodelamination” for the Management of Retinal Detachment Complicated by Proliferative Vitreoretinopathy. Retina. 2019;39 Suppl 1:S125-S128. Open Access Article Link: https://journals.lww.com/retinajournal/Fulltext/2019/10001/Single_Port_Vitrectomy_and__Oleodelamination__for.30.aspx#pdf-link Open Access Video Link: https://d047c2cddb.site.internapcdn.net/permalink/iae/a/iae_2017_04_20_snead_216-1031_sdc1.mp4 In this surgical technique special edition of RETINA: The Journal of […]

Cost Analysis of Pneumatic Retinopexy versus Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Written by: Daniel Su, MD November 2019 Elhusseiny AM, Yannuzzi NA, Smiddy WE. Cost Analysis of Pneumatic Retinopexy versus Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment. Ophthalmol Retina 2019;3:956–961 Rhegmatogenous retinal detachment (RRD) may result in significant and permanent vision loss. Many studies have looked at outcomes of various surgical techniques in achieving single surgical […]

Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials

Written by: Rehan M. Hussain, MD November 2019 Maguire, AM, Russell S, Wellman JA. Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials. Ophthalmology 2019 Sep;126(9):1273-1285.  doi: 10.1016/j.ophtha.2019.06.017. Published online Jun 22, 2019. Voretigene neparvovec (VN) is a non-replicating adeno-associated virus (AAV), which has […]

Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2

Written by: Akshay S. Thomas, MD October 2019 Chew EY, Clemons TE, Jaffe GJ, et al. Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial. Ophthalmology. 2019;126(4):540-549. Macular telangiectasia type 2 (MacTel 2) is an idiopathic condition without available treatment options which results in slowly […]

Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs. Aflibercept vs. Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial by the LEAVO Study Group

Written by: Avni P. Finn, MD October 2019 Hykin P, Prevost AT, Vasconcelos JC, et al. Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial. JAMA Ophthalmol. Published online August 29, 2019. doi:10.1001/jamaophthalmol.2019.3305 Visual impairment in central retinal vein occlusion (CRVO) due to […]